ExpressionAnalysis,FunctionalEnrichment,andNetworkInference
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Abriefhistoryofexpressionanalysis
Feb:CompletionoftheDraftHumanGenome
MolecularBiologyin7Words:
1Gene2RNA3Protein4Folding5Structure6Function7Regulation
TheGenomeProjecthasprovideda“partslist”forahumancell
Differentcelltypesexpressdifferentsetsofgenes
MethodsfordetectionofRNA
NorthernBlots
QuantitativeRT-PCR
Large-ScaleQuantitativeRT-PCR
Microarrays
RNA-Seq
DiseaseProgressionandPrecisionCare
1GeneticRisk
2EarlyDetection
3PatientStratification
4Diseasestaging
5TreatmentOptions
